#nootropics

Line chart showing a larger cognitive-performance gap between creatine and placebo groups under sleep deprivation than under normal rest
ResearchSupplements & Nootropics

What a Creatine and Cognition Review Actually Found

A systematic review of RCTs found creatine supplementation gave modest cognitive benefits, most consistently under cognitive stress like sleep deprivation, or in people with lower baseline creatine stores, such as vegetarians.

Meta-analysis
Stylised pill capsule half-filled with question marks, half with a checkmark pattern
ScienceSupplements & Nootropics

Do Nootropics Actually Work?

Some compounds marketed as nootropics have real trial support. Most of the 'stack' culture around them doesn't. Here's the difference.

Meta-analysis